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The Desmoid Tumor Research Foundation

March 2026

Old drug, new data: Broadening the therapeutic armamentarium for desmoid tumors

Author Information

Fahima Dossa 1, Silvia Stacchiotti 2, Alessandro Gronchi 3

1Cedars-Sinai Medical Center Los Angeles, California United States. 2Fondazione IRCCS Istituto Nazionale dei Tumori Milan Italy. 3Fondazione IRCCS Istituto Nazionale dei Tumori Milan, -- select state -- Italy.

Publication

Clin Cancer Res

Summary

Desmoid tumours are a locally invasive neoplasm that can exhibit unpredictable clinical behaviour. While treatment options are numerous, few are supported by level 1 evidence. A recent phase 3 trial evaluated the efficacy of long-used pegylated liposomal doxorubicin in patients with progressive desmoid tumours.

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