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International Research Workshops

2017 DTRF International Desmoid Tumor Research Workshop

 

Join us for the Fourth Annual DTRF International Desmoid Tumor Research Workshop in conjunction with the Annual DTRF Patient Meeting. This event will bring together a diverse group of scientists including the brightest minds in desmoid tumor research, human genetics, drug development and related fields.

 

Saturday, September 23, 2017, 12:30- 6pm- Annual DTRF Patient Meeting

Sunday, September 24, 2017, 8am- 4pm- DTRF International Desmoid Tumor Research Workshop

 

Both events will take place at the Sheraton Philadelphia Downtown Hotel in Philadelphia, PA.

View the list of current attendees and tentative agenda.

Register here for either or both events.

Research Workshops

On September 24, 2016, the DTRF hosted our third DTRF International Research Workshop with over 40 researchers in attendance from the United States, Europe and Asia. The presentations below were given at the Workshop.
 
 
View scientific abstracts and presentations here.
  • Benjamin Alman, MD, Department Chair, Orthopedic Surgery, Duke University, “Introduction and Report on Collaboration for a Cure project.”

 

  • Kris Vleminckx, PhD, Professor of Developmental Biology, Ghent University, “Identifying targets for therapy in a novel genetic Xenopus model for desmoid tumor formation. 

 

  • Stephen Horrigan, PhD, Chief Scientific Officer, BetaCat Pharmaceuticals, “Tegatrabetan (BC-2059) – A new approach to targeting beta catenin and Wnt activation.”

 

  • Danielle Braggio, PhD, Post-Doctoral Researcher, Ohio State University, “Initial studies of Tegatrabetan (BC-2059) in desmoid tumor cell strains.”

 

  • Mrinal Gounder, MD, Assistant Professor and Medical Oncologist, Memorial Sloan Kettering Cancer Center, “Development of PRO tool in desmoid tumors.”

 

  • Steven Attia, DO, Assistant Professor of Oncology, Mayo Clinic, A model for international, multi-institutional, multi-disciplinary sarcoma videoconferencing.”

 

  • Nicholas Penel, MD, PhD, Medical Oncology, Centre Oscar Lambret, “The French Patient Registry Project.”

 

  • Danique van Broekhoven, MD, Surgical Oncology, Erasmus MC, Outcome of non-surgical management of extra-abdominal and abdominal desmoid-type fibromatosis: a population based study.”

 

  • Matt van de Rijn, MD, PhD, Professor, Department of Pathology, Stanford University Medical Center, “Gene expression profiling of desmoid tumors.”

 

  • Danielle Braggio, PhD, Post-Doctoral Researcher, Ohio State University.

 

  • Lara Sullivan, MD, MBA, Vice President, Pfizer CURES, Pfizer, Inc., “Update on clinical trials on Pfizer compound/ a potential new treatment.”

 

  • Peter Hohenberger, MD, Mannheim University Medical Center, An analysis of incidence and significance of trauma prior to desmoid tumor formation.”

 

  • Nancy Cho, MD, Assistant Professor of Surgery, Harvard Medical School, “Targeting hyaluronic acid in desmoid tumors.”

 

  • Chiara Colombo, MD, Surgical Oncology, Instituto Tumori di Milano, Whole Exome Sequencing in patients under Wait & See (W&S): a preliminary analysis.”

 

  • Daniela Segat, PhD, Senior Researcher, ”Mauro Baschirotto” Institute for Rare Diseases – B.I.R.D. Foundation, In vitro studies of the microenvironmental factors responsible of the proliferation and aggressiveness of desmoid tumor cells.”   

View bios of our presenters and attendees here.

On October 18, 2015, we held our second DTRF International Research Workshop with over 40 researchers in attendance from the United States, Europe and Asia. View abstracts of the following presentations here.
  • Benjamin Alman, MD, Department Chair, Orthopedic Surgery, Duke University, Introduction and Report on Collaboration for a Cure project.

 

  • Alexander Lazar, MD, PhD, Director, Department of Pathology, MD Anderson Cancer Center Selective (Soft Tissue) Pathology Fellowship Training Program, “CTNNB1 Genotyping in Desmoid Tumors: Where Do We Stand?”

 

  • Danielle Braggio, PhD, Post-Doctoral Researcher, Ohio State University, “Reactivation of apoptosis as a potential therapeutic target for desmoid tumors with CTNNB1 S45F mutation.”

 

  • Radhika Atit, PhD, Associate Professor, Case Western Reserve University Dept of Biology, Case Western Reserve University, “Sustained β-catenin activity in dermal fibroblasts promotes fibrosis by regulating extracellular matrix protein-coding genes.”

 

  • Meredith K. Chuk, MD, Scientific Liaison for Sarcoma, Medical Officer, FDA, “A review of FDA draft guidance–Rare Diseases: Common Issues in Drug Development.”

 

  • Yoshihiro Nishida, MD, PhD, Chairperson, Associate Professor Dept. of Orthopaedic Surgery, Nagoya University, “Planned simple resection for selected patients with extra-peritoneal desmoid tumors.”

 

  • Alice Chen, MD, Investigational Drug Branch, NCI- NIH, “Phase II trial of PF-03084014 in adults with desmoid tumors/aggressive fibromatosis.”

 

  • Raphael Pollock, MD, PhD, Professor of Surgery; Director, Division of Surgical Oncology, Ohio State University Comprehensive Cancer Center, “Targeting the Notch Pathway: A Potential Therapeutic Approach for Desmoid Tumors.”

 

  • Mrinal Gounder, MD, Assistant Professor and Medical Oncologist at Memorial Sloan Kettering Cancer Center, Notch Inhibition in Desmoids: “Sure It Works in Practice, but Does it Work in Theory?”

 

  • Bernd Kasper, MD, PhD, Professor, Mannheim University Medical Center, Interdisciplinary Tumor Center, Sarcoma Unit, “Clinical and translational research results of a phase II study evaluating imatimib to induce progression arrest in RECIST progressive desmoid-type fibromatosis – A study of the German Interdisciplinary Sarcoma Group (GISG-01).”

 

  • Mushriq Al-Jazrawe, PhD Candidate, University of Toronto, Laboratory Medicine & Pathobiology, “Single cell-derived clonal analysis of desmoid tumors.”

 

  • Kelly Mercier, PhD, Research Chemist, Systems and Translational Science, NIH, Eastern Regional Comprehensive Metabolomics Core (RTI RCMRC), “Metabolomics: Moving Towards A Better Understanding of Desmoid Tumors.”

 

  • Ty Subhawong, MD, Musculoskeletal Radiology, Assistant Professor of Radiology University of Miami, “MRI features of response in systemic therapy for aggressive fibromatosis.”
View bios of our presenters and attendees here.
On September 28, 2014, we held our first DTRF International Research Workshop with over 20 researchers in attendance from the United States and Europe. It was a diverse group of scientists, including experts in desmoid tumor research, human genetics, drug development and related fields.

 

We had short presentations on the current state of desmoid tumor research, and devoted several hours to collaborative group discussions where we asked the important questions: What are the gaps in knowledge that we need to address next? How can we collaborate to move the science forward most efficiently, using the limited resources available? There were offers to pool resources and information, and ideas generated for new collaborative research. This is a hands-on workshop that produces practical results. We are excited to already have three projects that are being formulated to address very specific issues raised in the workshop.

 

The following institutions were represented at the 2014 Research Workshop:
  • Brigham & Women’s Hospital
  • Duke University
  • Fondazione IRCCS Istituto Nazionale dei Tumori
  • Lunenfeld-Tanenbaum Research Institute
  • MD Anderson Cancer Center
  • Memorial Sloan-Kettering Cancer Center
  • Mount Sinai Hospital, Toronto
  • National Cancer Institute (NCI)
  • National Institutes of Health (NIH)
  • Netherlands Cancer Institute
  • Ohio State Comprehensive Cancer Center
  • Stanford University
  • University of Miami
  • University of Toronto
  • U.S. Food and Drug Administration (FDA)
  • Vanderbilt University
  • Wake Forest University
View our Research Workshop pictures here.
 
View bios of our presenters and attendees here.
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