The Desmoid Tumor Research Foundation

February 2021

Intra-abdominal small intestinal desmoid tumour mimicking GIST

Author Information

Sai Krishna Eswaravaka(1), Swanit Hemant Deshpande(2), Roshan Chiranjeev(2), Jayashri Sanjay Pandya(2).

(1)Dept of General Surgery, Topiwala National Medical College, Mumbai, Maharashtra, India. (2)General Surgery, BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.

Publication

BMJ Case Rep

Summary

We report a case of a 31-year-old man presenting with abdominal mass associated with dyspepsia and early satiety. CT scan demonstrated a large heterogeneous mass adherent to or arising from the jejunum. The patient underwent a successful elective exploratory laparotomy with resection of the tumour arising from the wall of the ileum with a 10 cm margin. The patient had an uneventful recovery and no recurrence at 6-month follow-up. Pathology report and immunohistochemistry analysis revealed the mass to be a primary desmoid tumour of the small bowel, as the tumour was negative for c-kit and Discovered on GIST 1 (DOG-1) and positive for beta-catenin and smooth muscle actin.

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