Stable Disease

Disease “that is neither decreasing nor increasing in extent or severity.” (Source: National Cancer Institute)

Learn About Treatment & Monitoring

“A substance that blocks the action of enzymes called tyrosine kinases. Tyrosine kinases are a part of many cell functions, including cell signaling, growth, and division. These enzymes may be too active or found at high levels in some types of cancer cells, and blocking them may help keep cancer cells from growing. Some tyrosine kinase inhibitors are used to treat cancer. They are a type of targeted therapy.” (Source: National Cancer Institute)

Learn About Treatment & Monitoring

Volumetric medical imaging, such as CT, magnetic resonance imaging (MRI), or digital breast tomosynthesis (DBT), helps retain the 3D nature of the body’s internal structures by stacking multiple cross-sectional images.

The DTRF Radiomics Working Group is evaluating volumetrics as part of our efforts to define other imaging features beyond RECIST that can be used to better evaluate desmoid patient outcomes.

Learn About Treatment & Monitoring

Learn about the DTRF Radiomics Working Group

“High-intensity focused ultrasound (HIFU) is a minimally invasive medical procedure that uses ultrasound waves to treat certain conditions, such as tumors, uterine fibroids and tremor. The very high-intensity and highly focused sound waves interact with targeted tissues in your body to modify or destroy them.” (Source: Cleveland Clinic)

Learn About Treatment & Monitoring

APC is the acronym for the gene Adenomatous Polyposis Coli. “Mutations in the APC gene cause a group of polyposis conditions that have overlapping features including familial adenomatous polyposis[anchor link to FAP “Glossary” entry] (F.A.P) or Gardner syndrome which may include the development of desmoid tumors, ” (Source: National Organization for Rare Disorders (NORD))

Learn About Desmoid Tumors

Learn About Desmoid Tumors and Genetics

Active surveillance is the medical approach that carefully monitors a desmoid tumor through magnetic resonance imaging (MRI) or computed tomography (CT) scans to look for signs of progression or regression (shrinking).¹ Active surveillance is the well-established primary approach to most primary/recurrent sporadic/familial desmoid tumors, depending on location. The decision to proceed with active surveillance is on a case-by-case basis and should be discussed with your doctor. You and your care team may decide to pursue treatment at any point due to progression of the tumor or your symptoms.