The Desmoid Tumor Research Foundation

June 2016

Combination chemotherapy with methotrexate and vinblastine for surgically unresectable, aggressive fibromatosis.

Author Information

Chang Ho Kang,Jong Hoon Park,Kwan-Woo Kim,Kyong-Hwa Park,Kyung-Han Ro,Sang-Heon Song,Yoon Ji Choi

Department of Orthopedic Surgery, Korea University Anam Hospital, Seoul pjh1964@hanmail.net.,Department of Orthopedic Surgery, Korea University Anam Hospital, Seoul.,Department of Orthopedic Surgery, Myung Ji Hospital, Gyeonggi-do, Republic of Korea.,Department of Radiology, Korea University Anam Hospital, Seoul.,Division of Oncology/Hematology, Departments of Internal Medicine, Korea University Anam Hospital, Seoul.

Publication

Summary

Patients were enrolled if they were treated with methotrexate and vinblastine chemotherapy for recurrences after surgical excision or newly diagnosed aggressive fibromatosis that was not amenable to surgical resection at the Korea University Medical Center from May 2008 to February 2016. Low-dose chemotherapy with methotrexate and vinblastine for 1 year was effective and well tolerated by adult patients with aggressive, recurrent fibromatosis.

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