The Desmoid Tumor Research Foundation

March 2022

Desmoid-type fibromatosis of the breast: about two cases and literature review

Author Information

Laakom O (1), Bergaoui H (1), Hammouda SB (2), Khalfalli A (3), Njim L (2), Faleh R (1).

(1) Service de Gynécologie du Centre de Maternité et Néonatologie de Monastir, 5000, Tunisie. (2) Service d´Anatomie et Cytologie Pathologiques du CHU Fattouma Bourguiba Monastir, 5000, Tunisie. (3) Service de Radiologie B du Centre de Maternité et Néonatologie de Monastir, 5000, Tunisie.

Publication

Pan Afr Med J

Summary

Breast fibromatosis is a benign breast tumor of mesenchymal origin, accounting for 0.2% of breast tumors. This study reports two cases of breast fibromatosis highlighting its diagnostic, morphological, therapeutic and evolutionary features. In both cases, this tumor clinically and radiologically mimicked a cancer. Diagnostic confirmation was based on histological examination. Breast fibromatosis was characterized by local progression and a tendency to recurrence, hence the role of surgical excision with free surgical margins in our patients. The role of locoregional treatments (radiotherapy and cryotherapy) and medical treatments, in particular anti-estrogen therapy, is not clearly defined. In conclusion, breast fibromatosis must be known as it mimicks breast cancer and is characterized by a very high recurrence rate, without ever developing metastases.

View Abstract