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The Desmoid Tumor Research Foundation

September 2020

Desmoid-type fibromatosis of the lower extremity: A unique case of complete lesion resolution following core needle biopsy

Author Information

Tafti D(1), Kao E(2), Alderete JF(3), Cecava ND(4).

(1)Dept of Radiology, Brooke Army Medical Center, Fort Sam Houston, San Antonio, TX. (2)Dept of Pathology, Brooke Army Medical Center, Fort Sam Houston, San Antonio, TX. (3)Dept of Orthopaedics, Brooke Army Medical Center, Fort Sam Houston, San Antonio, TX; Baylor College of Medicine, Houston, TX. (4)Dept of Radiology, Brooke Army Medical Center, Fort Sam Houston, San Antonio, TX; Uniformed Services Univ of Health Sciences, Bethesda, MD; Texas A&M School of Medicine, Bryan, TX.

Publication

Clin Imaging

Summary

We present a case of a 50-year-old female with a left thigh vastus medialis intramuscular mass which underwent imaging work-up and subsequent core needle ultrasound-guided biopsy showing results of desmoid-type fibromatosis. Following biopsy, the tumor showed prompt, complete regression with complete MRI resolution 2 months following biopsy. The patient showed no evidence of disease recurrence out to one year on MRI surveillance. To our knowledge there have been no reported cases of DF spontaneous regression 2 months following a core needle biopsy. Understanding the variable behavior of desmoid-type fibromatosis can assist the radiologist in guiding management of these lesions with the goal of optimizing clinical outcomes and preventing unnecessary aggressive treatments for stable or regressing disease.

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