The Desmoid Tumor Research Foundation

February 2020

Giant Mesenteric Fibromatosis Associated with Non-Hodgkin Lymphoma. A Case Report and Literature Review (FULL ARTICLE)

Author Information

Pujol-Cano N(1), Bianchi A(1), Pagan-Pomar A(1), Ramos-Asensio R(2), Martinez-Ortega MA(2), Martinez-Corcoles JA(1), Gonzalez-Argente XF(1).

(1)Department of General Surgery, Hospital Universitario Son Espases, Palma de Mallorca, Spain (2)Department of Pathological Anatomy, Hospital Universitario Son Espases, Palma de Mallorca, Spain

Publication

EC Gastroenterology and Digestive System

Summary

We are discussing about a 40-year-old male presented with a concomitant diagnosis of non- Hodking lymphoma and mesenteric fibromatosis not associated with any of the risk factors mentioned above. CT and PET scan are performed visualizing a vascularized and well-defined mesenteric center- abdominal solid mass with hypermetabolism contacting with the gastric body, the duodenum, the body and the tail of the pancreas, the transverse colon and the spleen. Ultrasound-guided trucut biopsy showed features suggestive of mesenteric fibromatosis. Elective laparotomy was done and a giant mass arising from mesentery was excised including partial gastrectomy and segmental resection of the transverse colon. Distal pancreatectomy, small bowel resection and successive splenectomy are performed due to a large hypertensive component. The histopathology of the surgical pieces is compatible with intra-abdominal desmoid fibromatosis. As far as we know, it is the biggest case of mesenteric fibromatosis tumour excision reported in the literature. We also noticed that our case is the first reported case of concomitant presence of mesenteric fibromatosis and non-Hodgkin’s lymphoma that has not relation to any described risk factor. More research is needed to establish what type of association this presentation may indicate.

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