The Desmoid Tumor Research Foundation

May 2018

Ex vivo resection and intestinal autotransplantation for a large mesenteric desmoid tumor secondary to familial adenomatous polyposis: A case report and literature review

Author Information

Cheng C(1), Guo S(2), Kollie DEGB(1), Zhang W(3), Xiao J(3), Liu J(1), Lu X(1), Xiao Y(1).

(1)Department of Gastrointestinal Surgery. (2)Department of Pathology. (3)Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Publication

Medicine (Baltimore)

Summary

Here we present a rare case of a large mesenteric desmoid tumor secondary to familial adenomatous polyposis (FAP) in a 34-year-old man accepted the ex vivo resection, and intestinal autotransplantation. An en bloc resection (R0 resection), and an ex vivo resection followed by intestinal autotransplantation was performed. The patient was discharged from the hospital on the 25th day after the operation, and was regularly followed up after surgery with abdominal ultrasonography and laboratory-biochemical tests every month, and serial CT scans every 3 months which showed no evidence of tumor recurrence, thrombus, intestinal obstruction or abdominal infection so far. An ex vivo resection and intestinal autotransplantation appear feasible for cases with pathological lesions involving the vessels at the root of mesentry, and represents an attractive alternative for the management of mesenteric desmoid tumors.

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