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The Desmoid Tumor Research Foundation

March 2021

Aggressive fibromatosis of the right colon mimicking a gastrointestinal stromal tumour: a case report [Full Article]

Author Information

Jovanovic MM(1), Djuric-Stefanovic A(1,3), VelickovicD(2,3), Keramatollah E(2,3), Micev M(4), Jankovic A(1), Milosevic S(1), Kovac JD(1,3).

(1)Centre for Radiology and MRI, University Clinical Centre of Serbia, Belgrade, Serbia. (2)Faculty of Medicine, University of Belgrade, Belgrade, Serbia. (3)Clinic for Digestive Surgery, University Clinical Centre of Serbia, Belgrade, Serbia. (4)Institute of Pathology, University Clinical Centre of Serbia, Belgrade, Serbia.

Publication

J Int Med Res

Summary

This case report presents the radiological, intraoperative and histopathological findings from a 37-year-old female patient that presented with epigastric pain and a palpable mass in the right hemiabdomen. Histological and immunohistochemical examinations of the resected tumour, including positive staining for beta-catenin, confirmed a postoperative diagnosis of desmoid type fibromatosis. This specific case showed that desmoid type fibromatosis of the colon can mimic gastrointestinal stromal tumours (GIST) based on its clinical presentation, computed tomography and magnetic resonance imaging findings. Differential diagnosis between desmoid type fibromatosis and GIST is clinically very important due to the different treatments and follow-up protocols that are implemented for these lesions.

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