Clinicopathological Characteristics And Prognostic Factors For The Recurrence Of Abdominal Desmoid Tumors: Analysis Of 113 Patients From Two Chinses Hospitals (ENTIRE ARTICLE)

Summary

The purpose of the present study was to delineate the clinicopathologic features and explore the prognostic factors of abdominal desmoid tumors (ADTs). From January 2000 to January 2019, patients with ADTs who underwent macroscopically complete resection at the China National Cancer Center were included in the study. The clinicopathologic characteristics and follow-up data were carefully collected and reviewed. Prognostic factors such as age at presentation, sex, tumor location, tumor size and tumor proximity to nerves or vasculature were analyzed, and recurrence-free survival was analyzed with these factors. A total of 113 patients with ADTs were assigned to the abdominal wall group (n = 66) or abdominal cavity group (n = 47) according to the tumor site. Abdominal wall DTs and intra-abdominal DTs demonstrated distinct clinicopathological features and prognoses. During a median 61-month follow-up period, twelve (10.2%) patients had local recurrence. According to the univariate and multivariate analyses, intra-abdominal tumors, large tumors, and positive margins were independent risk factors for poor prognosis. Compared with intra-abdominal DTs, abdominal wall DTs demonstrate different clinicopathological features and a better prognosis. Under the premise of ensuring negative margins during the rst surgical procedure, patients with abdominal wall DTs can obtain satisfactory prognoses through radical resection.