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The Desmoid Tumor Research Foundation

March 2020

Colonic aggressive fibromatosis with perforation: a case report

Author Information

Chen G(1,3*), Lijian C(4*), Wu J(2*), Ren L(1,3), Wang H(1,3), Fan H(1,3), Zhou Y(1,3), Du Q(5), Wang Z(1,3), Zhang M(1), Jia F(1), Jia G(4).

Depts of (1)Hepatopancreatobiliary Surgery, (2)Oncology, The Affiliated Hospital of Qinghai Univ, Xining, Qinghai Province, China; (3)Qinghai Province Key Laboratory of Hydatid Disease Research, Xining, Qinghai Province, China; (4)Dept of General Surgery, Qinghai Renji Hospital, Xining, Qinghai Province, China; (5)Dept of General Surgery, Shanghai Fourth PeopleÂ’s Hospital Affiliated to Tongji Univ School of Medicine, Shanghai, China. *Equal contributors.

Publication

Int J Clin Exp Med 2020

Summary

Aggressive fibromatosis (AF) is a rare soft tissue tumor derived from mesenchymal tissue characterized by invasion into the surrounding muscle and soft tissue growth without distant metastasis. Although AF originates from the mesentery, omentum, and pelvis and has been described, primary AF originating from the colon has rarely been reported. In this case, an 18-year-old male patient with sudden left lower abdominal pain for 10 hours with nausea and vomiting was admitted to the hospital for an emergency medical examination. Imaging revealed a mass located near his sigmoid colon that was considered interstitial or malignant. The patient underwent urgent exploratory surgery, and perforation of the tumor was found. Histopathological examination showed that the tumor was colonic AF. Considering the patientÂ’s medical history of acute abdomen pain, we assume this to be a rare case of colonic AF with perforation.

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