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The Desmoid Tumor Research Foundation

July 2024

Contrast-enhanced ultrasonography combined with superb microvascular imaging for preoperative diagnosis of sporadic intra-abdominal desmoid-type fibromatosis: A case report

Author Information

Kazuhiro Komi 1 2, Minoru Fujita 3, Noriaki Manabe 3, Munenori Takaoka 4, Katsuya Kato 5, Hideyo Fujiwara 6, Takako Konishi 3 4, Emiko Bukeo 3, Hiraku Misawa 3, Jun Nakamura 3, Maki Ayaki 3 7, Takahisa Murao 8, Mitsuhiko Suehiro 9, Takashi Akiyama 6, Hirofumi Kawamoto 9, Tomoari Kamada 8, Atsushi Urakami 4, Yoshio Naomoto 4, Tomoki Yamatsuji 4, Takuya Moriya 2, Ken Haruma 9, Jiro Hata 10

1Center for Doctors' Career Development, Kawasaki Medical School Hospital, Kurashiki, Japan. 2Department of Pathology, Kawasaki Medical School Hospital, Kurashiki, Japan. 3Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School General Medical Center, Okayama, Japan. 4Department of General Surgery, Kawasaki Medical School General Medical Center, Okayama, Japan. 5Department of Diagnostic and Therapeutic Radiology, Kawasaki Medical School General Medical Center, Okayama, Japan. 6Department of Pathology, Kawasaki Medical School General Medical Center, Okayama, Japan. 7Department of Gastroenterology and Hepatology, HITO Medical Center, Shikokuchuou, Japan. 8Department of Health Care Medicine, Kawasaki Medical School General Medical Center, Okayama, Japan. 9Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, Okayama, Japan. 10Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School Hospital, Kurashiki, Japan.

Publication

Radiol Case Rep

Summary

We herein report a case of sporadic intra-abdominal desmoid-type fibromatosis in which contrast-enhanced ultrasonography (US) combined with superb microvascular imaging (SMI) was useful for preoperative diagnosis. 18-Fluorodeoxyglucose positron emission tomography performed for systematic screening for lung cancer revealed an abnormal accumulation in the abdominal cavity. Transabdominal US showed a tumor with a mixture of hypoechoic and hyperechoic areas. Contrast-enhanced US combined with SMI revealed dendritic blood flow signals and no abnormal vascular network within the tumor. Macroscopic examination of the resected specimen revealed a white tumor with relatively clear boundaries. Microscopic examination revealed spindle cells with poor atypia proliferating in bundles with collagenous stromal cells. Immunohistochemistry showed nuclear localization of beta-catenin within the tumor cells. From these findings, we finally diagnosed intra-abdominal desmoid-type fibromatosis. Contrast-enhanced US combined with SMI is useful for diagnosing intra-abdominal desmoid-type fibromatosis.

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