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The Desmoid Tumor Research Foundation

December 2018

Desmoid Fibromatosis Mimicking Metastatic Recurrence After Pancreatectomy for Pancreatic Adenocarcinoma

Author Information

Navin P(1), Lehrke HD(2), Schmitz JJ(1), Truty MJ(3), Moynagh MR(1).

(1)Dept of Radiology, Mayo Clinic, Rochester, MN. (2)Dept of Pathology, Mayo Clinic, Rochester, MN. (3)Dept of Surgery, Mayo Clinic, Rochester, MN.

Publication

Mayo Clin Proc Innov Qual Outcomes

Summary

We present 3 cases of desmoid fibromatosis post pancreatectomy for pancreatic adenocarcinoma. All cases occurred within 3 years of diagnosis of pancreatic cancer, with subsequent extensive diagnostic work-up to rule out metastatic disease. No relationship between pancreatic cancer and desmoid fibromatosis is documented in the literature, with a postulated connection via mutations on the Wnt/APC/Beta-catenin pathway.

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