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The Desmoid Tumor Research Foundation

January 2018

Desmoid Tumours of the extremity and trunk. A retrospective study of 44 patients

Author Information

Wirth L(1), Klein A(1), Baur-Melnyk A(2), Knosel T(3), Lindner LH(4), Roeder F(5)(6), Jansson V(1), Durr HR(1)

(1)Musculoskeletal Oncology, Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, Campus Grosshadern, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.(2)Institute of Radiology, Campus Grosshadern, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.(3)Institute of Institute of Pathology, Campus Grosshadern, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.(4)Department of Medicine III, Campus Grosshadern, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.(5)Department of Radiation Oncology, Campus Grosshadern, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.(6)CCU Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, All authors are part of the SarKUM, the Bone and Soft Tissue Tumor Center of the University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

Publication

BMC Musculoskelet Disord

Summary

The aim of this retrospective study was to analyze the local control rates focusing on the effect of surgical margins and radiotherapy. From 1981 to 2014, 44 patients had been treated. Fifty four therapies had been applied, in 50 cases surgery +/- radiation therapy, NSAIDs or chemotherapy. In 4 cases a conservative approach was chosen. Surgical margins are less important than keeping function. Radiotherapy might be an option in unresectable lesions, the role of adjuvant radiotherapy is controversially discussed.

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