Extra-abdominal Desmoid Tumor in a 23-Year-Old Male: A Case Report

Summary

Desmoid tumors are rare, locally aggressive neoplasms that can develop in various anatomical locations. Accurate diagnosis requires a high level of suspicion, as these tumors can resemble other soft tissue sarcomas. This case report discusses a 23-year-old male with a symptomatic thigh mass, highlighting the importance of biopsy and immunohistochemical staining to distinguish desmoid tumors from malignant tumors. We also examine genetic predispositions, evolving management strategies, and the potential of novel therapies such as nirogacestat. Due to the high recurrence rate and unpredictable nature of desmoid tumors, long-term monitoring and a multidisciplinary approach are essential for achieving optimal patient outcomes.