The Desmoid Tumor Research Foundation

January 2019

Gastric aggressive fibromatosis: report of a case and review of the literature

Author Information

Wang YK(1), Jiang B(2), Yang YC(2), Wang SN(3), Li YY(3), Meng NL(4), Yuan XT(4), Jiang RD(1), Li ZG(1).

(1)Dept of Pathology, S Medical Univ Shenzhen Hosp Shenzhen, Guangdong, CHN. (2)Dept of Pathology, 159 Hosp of PLA Zhumadian, CHN. (3)Shenzhen Polytechnic, School of Electronic & Communication Engineering Shenzhen, Guangdong, CHN. (4)Dept of Pathology, 150 Hosp of PLA Luoyang, CHN.

Publication

Int J Clin Exp Pathol

Summary

A 47-year-old man presented with nonspecific abdominal pain. Gastroscopy revealed stomach wall swelling. An antral gastrectomy was performed. Histological examination revealed spindle-shaped cells and morphology typical of aggressive fibromatosis. We performed a literature search to identify conditions with features similar to those of aggressive fibromatosis. Aggressive fibromatosis does not metastasize, but it is locally invasive and has a tendency to relapse; however, our patient has not had recurrence > 1 year after surgery. Aggressive fibromatosis of the stomach may be confused with an inflammatory fibroid polyp, a gastrointestinal stromal tumor, schwannoma, leiomyoma, inflammatory myofibroblastic tumor, scirrhous carcinoma of the stomach, follicular dendritic cell sarcoma, inflammatory malignant fibrous histiocytoma, myofibroma/myofibromatosis, and solitary fibrous tumor of the stomach. Aggressive fibromatosis of the stomach is a rare spindle cell tumor that must be differentiated from a variety of conditions.

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