The Desmoid Tumor Research Foundation

September 2015

Intrathoracic Desmoid Tumor

Author Information

D'Hooghe L(1), Dekeyzer S(1), Dewaele T(1), Gieraerts K(2), Coenegrachts K(2).

(1)Dept of Radiology and Medical Imaging, University Hospital Ghent, Ghent, Belgium. (2)Dept of Radiology and Medical Imaging, AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium.

Publication

J Belg Soc Radiol

Summary

A 47-year-old female was referred to the hospital because of persistent pain at the ventral right side of the chest for several weeks. Contrast-enhanced CT of the chest confirmed the presence of a right-sided sharply delineated heterogeneous intra-thoracic mass with a broad pleural base. Because malignancy could still not be ruled out, a surgical biopsy was performed. Pathologic examination showed a fibromatous spindle cell lesion without signs of high grade malignancy. Histological and immunohistochemical image was strongly suggestive for desmoid tumor with staining negative for keratin, CD34 and S100 and positive for beta-catenin and actin. Surgery was recommended, but the patient rejected and chose radiotherapy. Follow-up imaging six months later showed slight volume loss of the tumor. The patient remains in further follow-up.

View Abstract