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The Desmoid Tumor Research Foundation

December 2020

Long-term follow up of a patient with a recurrent desmoid tumor that was successfully treated with proton beam therapy: A case report and literature review

Author Information

Sawada T(1), Mizumoto M(1), Oshiro Y(1,2), Numajiri H(1), Shimizu S(1), Hiroshima Y(1), Nakamura M(1), Iizumi T(1), Okumura T(1), Sakurai H(1).

(1)Faculty of Medicine, Univ of Aleppo, Aleppo, Syria. (2)Dept of Pathology, Aleppo Univ Hospital, Aleppo, Syria. (3)Pediatric Dept, Aleppo Univ Hospital, Aleppo, Syria.

Publication

Clin Transl Rad Onc

Summary

We treated a male patient with a head and neck recurrent desmoid tumor with proton beam therapy (PBT) at a dose of 60 Gy (RBE). This patient underwent surgical resection as initial treatment, but the tumor recurred only six months after surgery, and resection was performed again. After PBT, the tumor gradually shrank and complete remission has been achieved for 10 years without any severe late toxicity. Here, we report the details of this case, with a review of the literature. We suggest that PBT may reduce the incidence of second malignant tumors by reducing the dose exposure around the planning target volume.

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