The Desmoid Tumor Research Foundation

January 2020

Tamoxifen Retinopathy During Treatment of an Inoperable Desmoid Tumor

Author Information

Furst M, Somogyi MB, Wong RW, Araujo D, Harper CA 3rd

School of Medicine, University of Texas Health at San Antonio, San Antonio, Texas; TOC Eye and Face, Austin, Texas; Austin Retina Associates, Austin, Texas; Department of Surgery and Perioperative Services, Dell Medical School, University of Texas at Austin, Austin, Texas; and Department of Sarcoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Publication

Retin Cases Brief Rep

Summary

Tamoxifen retinopathy is a condition rarely observed in clinical practice. Although tamoxifen is typically a treatment for breast cancer patients, we present a 68-year-old woman taking tamoxifen for an inoperable desmoid tumor, an equally rare condition. She presented with bilaterally deteriorating vision over the course of a year. Her vision remained stable 3 months after the cessation of tamoxifen. With the use of long-term tamoxifen as a primary treatment, we recommend screening at regular intervals by an ophthalmologist as an integral part of treatment.

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