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The Desmoid Tumor Research Foundation

February 2016

The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification.

Author Information

Andrew Churg,Francoise Galateau-Salle,Victor Roggli,William D Travis

Department of Pathology, Centre Hospitalier Universitaire Caen, Caen, France; Department of Biopathology, Centre Leon Berard, Lyon, France.,Department of Pathology, Duke University Medical Center, Durham, NC, USA.,Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: travisw@mskcc.org.,Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada.

Publication

Summary

A new World Health Organization (WHO) Classification of Tumors of the Pleura has recently been published. While the histologic classification of pleural malignant mesothelioma remains the same in the 2015 WHO classification as it was in the 2004 classification, multiple new observations have been recorded. Desmoid type fibromatosis, a locally aggressive tumor that can present in the pleura, has been shown to frequently have CTNNB1 gene mutations and express β-catenin by immunohistochemistry.

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