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The Desmoid Tumor Research Foundation

April 2019

Treatment of Desmoid Tumors in 2019

Author Information

Gronchi A(1), Jones RL(2).

(1)Dept of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. (2)Sarcoma Unit, Royal Marsden Hospital, Institute of Cancer Research, Fulham Road, London.

Publication

JAMA Oncol

Summary

Recently, there has been a paradigm shift in the treatment of Desmoid Tumor toward an initial approach of active surveillance, rather than surgery with or without radiation. This shift occurred because the behavior of DT is unpredictable, and spontaneous growth arrest and regression can occur. In addition, patients can be asymptomatic. Herein, we describe our approach to the management of DT and the evidence base for selecting therapies in specific clinical scenarios.

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