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The Desmoid Tumor Research Foundation

November 2019

Value of imaging findings in predicting post-operative recurrence of desmoid-type fibromatosis

Author Information

Wang J(1), Huang Y(2), Sun Y(2), Ge Y(3), Zhang M(1).

(1)Dept of Rad, The Second Affiliated Hosp of Zhejiang Univ, Hangzhou, Zhejiang, P.R. CHN. (2)Dept of Rad, The First Hosp of Jiaxing, First Affiliated Hosp of Jiaxing Univ, Jiaxing, Zhejiang, P.R. CHN. (3)Dept of Rad, The Affiliated Hosp of Jiangnan Univ, Wuxi, Jiangsu, P.R. CHN.

Publication

Oncol Lett

Summary

The present study aimed to predict the recurrence rate and time by retrospectively analyzing the clinical data (sex, age and recurrence time), imaging findings [tumor location, maximum diameter, border, computed tomography (CT) enhancement ratio, magnetic resonance enhancement ratio and T2 signal ratio] and pathological features (Ki-67 and microscopic margin) in a total of 102 cases of pathologically confirmed desmoid-type fibromatosis. The cohort comprised of 73 females and 29 males, with mean age of 32.86ñ12.64 years (range, 6-78 years). The 1-year and 2-year recurrence rate was 31 and 54%, respectively. Univariate analysis indicated that sex, maximum tumor diameter, CT enhancement ratio and Ki-67 had a significant effect on the recurrence time. Furthermore, multivariate analysis revealed that sex, maximum tumor diameter, Ki-67 and T2 signal ratio were independently associated with the time of recurrence, and the risk ratios were 0.424, 1.100, 1.084 and 1.268, respectively. Therefore, in male patients with a larger maximum tumor diameter, positivity for Ki-67 and a higher T2 signal ratio, desmoid-type fibromatosis was more likely to recur after surgery.

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