Dept of Radiology, The Second Affiliated Hospital of Zhejiang Univ, Hangzhou, Zhejiang 310009, P.R. China, Dept of Radiology, The First Hospital of Jiaxing, First Affiliated Hospital of Jiaxing Univ, Jiaxing, Zhejiang 314000, P.R. China, Dept of Radiology, The Affiliated Hospital of Jiangnan Univ, Wuxi, Jiangsu 214062, P.R. China.
Publication
Onc Letters
Summary
The present study aimed to predict the recurrence rate and time by retrospectively analyzing the clinical data (sex, age and recurrence time), imaging findings [tumor location, maximum diameter, border, computed tomography (CT) enhancement ratio, magnetic resonance enhancement ratio and T2 signal ratio] and pathological features (Ki‑67 and microscopic margin) in a total of 102 cases of pathologically confirmed desmoid‑type fibromatosis. The cohort comprised of 73 females and 29 males, with mean age of 32.86±12.64 years (range, 6‑78 years). The 1‑year and 2‑year recurrence rate was 31 and 54%, respectively. The median age at recurrence was 29 years. Univariate analysis indicated that sex, maximum tumor diameter, CT enhancement ratio and Ki‑67 had a significant effect on the recurrence time. Furthermore, multivariate analysis revealed that sex, maximum tumor diameter, Ki‑67 and T2 signal ratio were independently associated with the time of recurrence, and the risk ratios were 0.424, 1.100, 1.084 and 1.268, respectively. Therefore, in male patients with a larger maximum tumor diameter, positivity for Ki‑67 and a higher T2 signal ratio, desmoid‑type fibromatosis was more likely to recur after surgery.
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