The Desmoid Tumor Research Foundation

April 2014

Wait-and-See Policy as a First-Line Management for Extra-Abdominal Desmoid Tumors.

Author Information

Axelle Bertrand-Vasseur,David Biau,François Gouin,Frédérique Larousserie,Olivier Barbier,Philippe Anract,Sylvain Briand

Department of Orthopaedic Surgery, Begin Military Hospital, 69 avenue de Paris, 94163 Saint Mandé, France. E-mail address:olive.barbier@gmail.com.,Departments of Orthopaedic Surgery (D.B. and P.A.) and Pathology (F.L.), Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université Paris Descartes, Sorbonne Paris Cité, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France. E-mail address for D. B.,Departments of Orthopaedic Surgery (S.B. and F.G.) and Radiology (A.B.-V.), The University Hospital of Nantes, National Institute of Health and Medical Research, UMR-S 957, 1 Place Alexis Ricordeau, 44093 Nantes, France. E-mail address for S. Briand: sylv.

Publication

Summary

The disappointing results of current treatments and the ability of extra-abdominal desmoid tumors to spontaneously stabilize have increasingly drawn interest toward conservative management. The objective of this study was to evaluate a wait-and-see policy as a first-line management for extra-abdominal desmoid tumors. This two-center retrospective study involved fifty-five patients with a histologically proven extra-abdominal desmoid tumor. The primary outcome was the cumulative probability of dropping out from the wait-and-see policy. The wait-and-see policy included aggressive management of symptoms. We conducted a review of the relevant published series in which a watchful-waiting strategy was used. The cumulative probability of dropping out from the wait-and-see policy was 9.6% at the time of the last follow-up. A wait-and-see policy is an effective front-line management for patients with primary or recurrent extra-abdominal desmoid tumor.

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